Journal of Applied Biosciences (J. Appl. Biosci.) [ISSN 1997 - 5902]
Volume 46: 3081 - 3085. Published October 28, 2011.
Field efficacy and prophylaxis of extra – label 0.5 % moxidectin pour–on in a flock of sheep naturally infested with sarcoptes scabiei
1Danbirni, S., 2Natala*, A.J., 3Pewan, S.B., 3Barde, I.J. and 1Sackey, A.K.B.
1Department of Veterinary Surgery and Medicine, Faculty of Veterinary Medicine, Ahmadu Bello University, Zaria, Nigeria.
2Department of Veterinary Parasitology and Entomology, Faculty of Veterinary Medicine, Ahmadu Bello University, Zaria, Nigeria.
3National Veterinary Research Institute, Vom, Plateau State, Nigeria.
ABSTRACT
Objective: This study was carried out to investigate the efficacy and prophylaxis of extra-label 0.5 % Moxidectin pour-on in a flock of 28 sheep, 14 of which were naturally infested with Sarcoptes scabiei. Methodology and results: The infested sheep were divided into 2 groups of 7 sheep each. The first group (therapeutic group) was treated with the drug at the dosage of 0.5 mg kg-1 twice 14 days apart while the second group served as the infested control (no treatment). The 14 uninfested sheep were also divided into 2 groups of 7 each. The first group was prophylactically treated with the pour-on once on day 0, while the second group served as the uninfested control (no treatment). Skin scrapings of all the sheep were checked for the presence of mites a day to the treatment and skin lesions scored from 0-3. The result showed for the first time, that extra-label applications of 0.5 % Moxidectin pour-on cures and protects against Sarcoptic mange in sheep.
Conclusion and Application: This research has shown that Moxidectin can be used for both curative and prophylactic treatment of mange in Nigerian indigenous sheep.
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