Journal of Animal and Plant Sciences
J. Anim. Plant Sci. [ISSN 2071 - 7024]
Volume 5 (1): 406 - 413. Published November 23, 2009.
Evaluation in vitroof antiplasmodial activity of ethanolic extracts of Funtumia elastica, Rauvolfia vomitoria and Zanthoxylum gilletii on Plasmodium falciparum isolates from Côte-d’Ivoire
ZIRIHI Guédé Noël*, N'GUESSAN Koffi*^, ETIEN Dibié Théodore* and SERI-KOUASSI Badama Ph**.
*Université de Cocody-Abidjan (Côte-d’Ivoire) ; Unité de Formation et de Recherche (U.F.R.) Biosciences ; Laboratoire de Botanique ; 22 BP 582 Abidjan 22 ; **Université de Cocody-Abidjan (Côte-d’Ivoire) ; Unité de Formation et de Recherche (U.F.R.) Biosciences ; Laboratoire de Biologie Animale ; 22 BP 582 Abidjan 22.
^Corresponding author e-mail: nguessankoffifr@yahoo.fr
SUMMARY
The ethanolic extracts of Zanthoxylum gilletii (GZA), Funtumia elastica (EFU) and Rauvolfia vomitoria (VRA) were tested for effect on the in vitro growth of Plasmodium falciparum isolates (IS1, IS2 and IS3) according to the isotopic variant of microtest. The isolates were obtained from patients who came for consultation at the National Institute of Public health, in Abidjan (Côte-d'Ivoire). The isolates were maintained in culture using the method of Trager and Jensen in the presence of variable concentrations of chloroquine and extracts of plants (GZA, EFU and VRA) from the Ivorian traditional medicines. The values of IC50 (concentration inhibiting 50 % of the growth of parasites) showed that extracts of these plants have very strong antiplasmodial action.
Key words
Antiplamodial activity, Plasmodium falciparum; In Vitro Test, Côte-d'Ivoire
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